On the surface, chronic kidney disease-associated pruritus is just an itch. But for patients living with CKD-associated pruritus, the consequences are much more.1-5

Browse further to discover how CKD-aP may be affecting your patients’ quality of life,  mental health and even life expectancy.1–5

Are your patients
suffering in silence?
Up to 67% of haemodialysis patients are suffering from CKD-associated pruritus1

Your haemodialysis patients may be suffering in silence with CKD-aP.1 Learn about CKD-aP to help understand an important concern about their haemodialysis.7

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Still, there are times when my itching feels overpowering, when I say to myself it’s really terrible right now.”

– CKD-aP patient on haemodialysis, Germany

When CKD-associated pruritus becomes more than just an itch
The itch with life-changing consequences

CKD patients undergoing haemodialysis already have a poor quality of life, which is exacerbated by CKD-associated pruritus.2–4 Uncover how CKD-aP could be affecting your haemodialysis patients’ sleep quality, quality of life and mental health.2–3

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I’m scratching all the time, you can’t help it. I can’t sleep at night because it’s there twenty-four hours a day.”

– CKD-aP patient on haemodialysis, UK

The impact of CKD-associated pruritus lies beneath the surface
The impact of CKD-associated pruritus lies beneath the surface

CKD-aP can have a serious impact on health outcomes as well as higher drug utilisation.1,2,5,6 Look beneath the surface to discover the consequences of CKD-aP.1

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Sometimes I could just literally scratch myself to death”

– CKD-aP patient on haemodialysis, Australia

References & footnotes
References
  1. Sukul N, Karaboyas A, Csomor P, et al. Self-reported pruritus and clinical, dialysis-related, and patient-reported outcomes in hemodialysis patients. Kidney Medicine. (2020);3(1):42–53.e1.
  2. Ramakrishnan K, Bond TC, Claxton A, et al. Clinical characteristics and outcomes of end-stage renal disease patients with self-reported pruritus symptoms. Int J Nephrol Renovasc Dis. (2013);7:1–12.
  3. Shirazian S, Aina O, Park Y, et al. Chronic kidney disease-associated pruritus: impact on quality of life and current management challenges. Int J Nephrol Renovasc Dis. (2017);10:11–26.
  4. Pisoni R, Wikström B,  Elder S, et al. Pruritus in haemodialysis patients: international results from the Dialysis Outcomes and Practice Patterns Study (DOPPS). Nephrol Dial Transplant. (2006);21:3495–3505.
  5. Narita I, Alchi B, Omori K, et al. Etiology and prognostic significance of severe uremic pruritus in chronic hemodialysis patients. Kidney Int. (2006);69(9):1626–1632.
  6. Tsai YC, Hung CC, Hwang SJ, et al. Quality of life predicts risks of end-stage renal disease and mortality in patients with chronic kidney disease. Nephrol Dial Transplant. (2010);25:1621–1626.
  7. Yosipovitch G,  Zucker I,  Boner G, et al. A questionnaire for the assessment of pruritus: validation in uremic patients. Acta Derm Venereol. (2001);81:108–111.
  8. Millington G,  Collins A,  Lovell C, et al. British Association of Dermatologists’ guidelines for the investigation and management of generalized pruritus in adults without an underlying dermatosis, 2018. Br J Dermatol. (2018);178(1):34–60.
  9. Verduzco H, Shirazian S. CKD-associated pruritus: new insights into diagnosis, pathogenesis, and management. Kidney Int Rep. (2020);5(9):1387-1402.
  10.  Silverberg J, Kantor R, Dalal P et al. et al, A Comprehensive conceptual model of the experience of chronic itch in adults. AM J Clin Dermatol. (2018);19(5):759-769.